A team of scientists say it is “beyond reasonable doubt” the Covid pandemic started with infected animals sold at a market, rather than a laboratory leak.

They were analysing hundreds of samples collected from Wuhan, China, in January 2020.

The results identify a shortlist of animals – including racoon dogs, civets and bamboo rats – as potential sources of the pandemic.

Despite even highlighting one market stall as a hotspot of both animals and coronavirus, the study cannot provide definitive proof.

The samples were collected by Chinese officials in the early stages of Covid and are one of the most scientifically valuable sources of information on the origins of the pandemic.

Their analysis was published last year and the raw data made available to other scientists. Now a team in the US and France says they have performed even more advanced genetic analyses to peer deeper into Covid’s early days.

  • lunarul@lemmy.world
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    2 months ago

    Wasn’t this known already? Weren’t there all kinds of discussions about shutting down wet markets because of this?

    • jonne@infosec.pub
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      There’s a bunch of indications / conspiracy theories that it might have been a lab leak. Basically there’s not really a way to know unless the Chinese government starts being more forthcoming with information.

      The main reason the conspiracy theory started is because the city where it started had a world renowned virus research facility in it.

      Of course, the reason the facility is there in the first place is because Wuhan province is a place where a lot of viruses originate naturally (in bat colonies), so it makes sense you research the viruses close to their natural reservoir.

    • mlg@lemmy.world
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      Yeah but the US media was too busy implying that China manufactured the virus in a bio lab.

      Funnily enough China still suffered because it failed to lock down early enough because the government tried to ignore and detain doctors in an effort to control the narrative that everything would be fine.

      The US suffered because they nuked their Pandemic emergency pla only like a few years before covid because Trump thought Spanish Fever wouldn’t reincarnate to finish the job on its 100th anniversary lol.

      So it was easy to vaguely point at China instead of actually solving the problem.

    • The Octonaut@mander.xyz
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      2 months ago

      Wasn’t this disproven already? Covid has been detected in human waste matter samples from Autumn 2019 in Italy.

      Overall, the results of this blind retesting of a selected set of samples indicate the presence of SARS-CoV-2 antibodies in some SMILE samples collected in the prepandemic period. The oldest samples found positive for IgM by both laboratories were collected on 10 October 2019 (Lombardy), 11 November 2019 (Lombardy) and 5 February 2020 (Lazio), the latter with neutralizing antibodies. Two additional samples collected on 17 December 2019 (Campania) and 28 January 2020 (Lombardy) tested as IgG positive by VisMederi and positive for IgG S1 and IgG S1+NP by Erasmus. Additional IgM positive cases could have been detected also by Erasmus by lowering the cut-off of the commercial IgM assay. The older among these putative additional IgM positive samples was collected on 3 September 2019 in the Veneto region, one of the first and mostly severely affected COVID-19 regions.

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778320/

      • fine_sandy_bottom@lemmy.federate.cc
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        I don’t really understand what this is actually saying?

        Surely, if this were saying “covid started in italy” or “covid was around in 2019” that would rate more song and dance than a single obscure research paper?

        • Knock_Knock_Lemmy_In@lemmy.world
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          These findings do not at all suggest that the virus originated in Italy, but they endorse the idea that the virus was likely spreading in China before the first known cases and that could have been circulated by travelers given direct the connections between China and European and US countries, particularly the Northern West and East Italian regions, which are among the most industrialized and connected areas of Italy.

        • The Octonaut@mander.xyz
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          There’s a lot more than a single obscure research paper but that’s the best one in terms of science in my opinion. It was quite broadly covered news (in Europe at least?) when the virus was first found in waste water samples from Milan from the same period.

          We knew it was in Europe before 2020 all the way back in June 2020: https://www.reuters.com/article/business/healthcare-pharmaceuticals/italy-sewage-study-suggests-covid-19-was-there-in-december-2019-idUSKBN23Q1J8/

          By November 2020 it was pushed back as far as September 2019: https://newseu.cgtn.com/news/2020-11-17/COVID-19-was-spreading-in-Italy-by-September-2019-study-indicates-VuSqUttP8s/index.html

          As someone else replied, it isn’t saying Covid started in Italy, but rather that it definitely didn’t start because someone ate bat soup from a wet market in Wuhan in December 2019. Well, the science is just stating as a fact that Covid was in these samples from Italy in 2019. Everything else is inferred.

          It was 2020. We had people shouting about “the China Virus” and others defending the cultural importance of wet markets and others saying it was a bioweapon from a lab and others saying it didn’t exist at all.

          It seemed to suit absolutely nobody’s narrative that

          • it took longer to be detected than previously thought, and lots of doctors missed it
          • we don’t really know where it started exactly, and can’t really ever know without a concerted investigation of the same sort done in Italy
          • international travel and globalisation as well as illegal trade of exotic animals and their carcasses makes it all pretty much guesswork, since Indonesian civit poachers on Filipino boats in the South China Sea don’t submit wastewater samples
          • ultimately its source was inconsequential compared to how we actually responded and what we retained afterwards (nothing, it seems)
  • RubberDuck@lemmy.world
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    2 months ago

    I’m not into conspiracy theories, but I find the confidence that is used in the defense of this origin just as Shakey as the lab leak theory.

    The lab location and research done means there is a lot of potential incentive for the Chinese government, the lab and even researchers in the field to not have it be a lab leak… As this would potentially cause an entire (important) field of study and their methods be regulated into oblivion by poorly written knee jerk laws.

    I’m fine with this as the accepted consensus on the subject, but I’ll keep my reservations for whatever good those do me.

    So how’s the abolishing of wet markets going? And the reduction of antibiotics use in industrial scale farming?

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        People have been saying for decades before covid that the wet markets were a ticking time bomb. There has probably been viral outbreaks in the past, but the local population could have died off before it spread.

        I think a lab leak of a natural virus is plausible, but irrelevant.

        • Knock_Knock_Lemmy_In@lemmy.world
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          I think lax saftey when experimenting with highly infectious coronaviruses is very relevant.

          Either improve the protocols or don’t experiment.

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            There’s a difference between lax safety and conspiracy to engineer a bioweapon. The main motivator of people pushing the Lab Leak conspiracy is that they want some villain to blame all this on.

            • Knock_Knock_Lemmy_In@lemmy.world
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              Not bioweapons. Covid isn’t dangerous enough.

              The prime conspiracy theory target is Anthony Fauci because some EcoHealth Alliance / NIH coronaviruses bat funding went to the Wuhan Institute of Virology.

              But you don’t need to subscribe to the Fauci Supervillan theory to suspect an accidental lab leak. China has already had 3 (2004, 2016, 2020) in this list. Pointing this out is not sino bashing (look at the number of US incidents). Accidental lab leaks happen all too regularly.

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                Back to an earlier point you made, how is it relevant that it was an accidental lab leak anymore? It’s China, they’ve either made better safe guards against possible break outs or made superficial changes for appearances. The international community can’t punish them for an accident that also hurt themselves. Hell, we can’t seem to keep their coast guard from ramming other ships.

                • Knock_Knock_Lemmy_In@lemmy.world
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                  how is it relevant that it was an accidental lab leak anymore?

                  Accidental lab leaks unfortunately happen. What is still relevant are the implications. The existence of the virus itself and it’s cover up are the problem.

                  The cover up

                  Mainstream media labeled anyone who mentioned the lab as a racist conspiracy theorists. Commenting on social media resulted in censorship.

                  WHO “invesigation” and Peter Daszak investigating himself.

                  Deletion of data from the WIV website.

                  Chinese closed policy and destruction of evidence.

                  No questioning science

                  Nature published a peer review saying that a lab origin was impossible.

                  Scientists hypothesising about lab origins were ostracised.

                  Source of the virus

                  In the wild, the nearest documented virus is 96% similar. Where have the 4% changes in the leaked version come from?

                  Have these 4% changes come from purposeful gain of function research?

                  Gain of function research in the US was banned in 2014. Did research stop or did funding just move countries?

                  Where else is secret GoF research being conducted? Is there sufficient saftey and oversight?

            • RubberDuck@lemmy.world
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              Bioweapon is also a strawman in this case, he did not say that.

              In gain of function research more virulent strains are made to study and find cures against. So we have a better understanding of how these viruses mutate, what makes them tick and how we can disrupt that.

              Noone would intentionally set something like that loose.

              • Duamerthrax@lemmy.world
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                There are definitely people saying that covid was an engineered bioweapon and the people saying that have a huge overlap with the people saying that it was a lab leak. Conspiracy theorists need a villain with a plan to make sense of the work and that’s why the lab leak theory keeps coming up.

      • crashfrog@sopuli.xyz
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        There are wet markets all over China and have been for…ever?

        Sure, and they all result in zoonotic illness.

    • nexusband@lemmy.world
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      I still believe it isn’t that far fetched that they disposed some kind of experiment/test from the labs on the market…

    • crashfrog@sopuli.xyz
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      The lab location and research done means there is a lot of potential incentive for the Chinese government, the lab and even researchers in the field to not have it be a lab leak…

      They also have incentive for the origin not to be a live animal market that they very publicly had claimed to have already shut down.

      It’s equally embarrassing either way, so the embarrassment proves nothing.

      • massacre@lemmy.world
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        Equally embarrassing? Doubtful. One is a market which can be blamed on illegal activity even after being shut down and ‘little’ people arrested. One represents Chinas first foray into LVL 4 containment bio research and cost billions to build and government officials would have to be held accountable and foreign science assistance to that research program likely cuts off… I’m not pleading the case of a conspiracy theory here, but the lab’s proximity to the outbreak is incredibly suspect.

        • crashfrog@sopuli.xyz
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          Equally embarrassing? Doubtful.

          Why does it have to be equally embarrassing? It just has to be embarrassing enough that they’d take steps to conceal it. Which they did. It doesn’t have to be the most embarrassing situation, just one of the ones that would spur them to act.

          One is a market which can be blamed on illegal activity even after being shut down and ‘little’ people arrested.

          But they did shut it down and they did arrest people and they even seized and incinerated every animal at the market without taking samples or even identifying and logging the species.

          On the other hand they didn’t shut down WIV, or really do anything to it at all.

          but the lab’s proximity to the outbreak is incredibly suspect.

          It’s 8km away, across a river.

          • massacre@lemmy.world
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            My point is they had a vested interest in the scapegoat excuse. The market is a mild embarassment compared to a possible containment breach. Not taking samples of the meat and cataloging everything actually compounds the scenario. Also if for example a CDC or USAMRIID site was ‘only’ 8 km away from an outbreak of a disease they were studying, it would trigger a full on investigation and full genetic comparison. Also they would be looking at any scientist as a vector. People live near where they work. Someone accidentally exposed could easily carry out daily activity in the vicinity while contagious.

            • crashfrog@sopuli.xyz
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              My point is they had a vested interest in the scapegoat excuse. The market is a mild embarassment compared to a possible containment breach.

              Ok, and I asked you why that matters. And you haven’t said.

              Also if for example a CDC or USAMRIID site was ‘only’ 8 km away from an outbreak of a disease they were studying, it would trigger a full on investigation and full genetic comparison.

              Well, but no, it doesn’t. For instance the CDC’s Enteric Diseases lab is in Atlanta, Georgia; it hosts the largest tissue collection of foodborne disease isolates in the world. If you were ever hospitalized for listeriosis in the United States, a sample of your disease isolate is probably located in a freezer there.

              And also people periodically get food poisoning from Atlanta restaurants. About 12 a year, let’s say.

              So every one of those food poisoning cases happens within 8 km of the largest food poisoning lab in the United States. Do you know how often they investigate whether the isolate leaked from the CDC lab?

              Literally never. Not ever. Because there’s no reason to, because people getting a disease near where the disease is studied is not statistically significant in any way.

              • massacre@lemmy.world
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                My point is they had a vested interest in the scapegoat excuse. The market is a mild embarassment compared to a possible containment breach.

                Ok, and I asked you why that matters. And you haven’t said.

                I’ve been thinking how to best respond to you at this point after looking at some of your response history. I can’t tell if you revel in pedantry or are just a troll. So I’ll give it one more go. I LITERALLY (since I know you like to poke holes in people using this word) state in the sentence you quote that the PROC has a vested interest in a scapegoat excuse of a wet market that they “embarassingly” (full air quotes) didn’t quite shut down vs. a leak from their only LVL 4 lab that relies on international support. Oh and the little matter of saving face by blaming a world wide pandemic on random chance vs. their own negligence.

                If you are really asking why that matters, let me spell it out: One embarassment is not the same as the other. They are orders of magnitude apart. Not to mention my other comment that their destruction of evidence and refusal to investigate applies even more suspicion and logically undermines their prevailing explaination of the wet market. the PROC certainly has more embarassing things like Tofu Dregs that they also have been unable to stop due to corruption, and largely the international community doesn’t care, but feels bad for the populace who have their lives or life savings destroyed. Do you believe that wet markets which have been a known to the west for ages and China’s inability to stop a populace with a cultural connection to them is so embarassing as to “cover it all up” and do so pretty visibly on the international stage>? So much for embarassing when they have a tight lock on news that gets out! I don’t believe a rational person can say yes to that.

                Also if for example a CDC or USAMRIID site was ‘only’ 8 km away from an outbreak of a disease they were studying, it would trigger a full on investigation and full genetic comparison.

                Well, but no, it doesn’t. For instance the CDC’s Enteric Diseases lab is in Atlanta, Georgia; it hosts the largest tissue collection of foodborne disease isolates in the world. If you were ever hospitalized for listeriosis in the United States, a sample of your disease isolate is probably located in a freezer there.

                And also people periodically get food poisoning from Atlanta restaurants. About 12 a year, let’s say.

                So every one of those food poisoning cases happens within 8 km of the largest food poisoning lab in the United States. Do you know how often they investigate whether the isolate leaked from the CDC lab?

                Literally never. Not ever. Because there’s no reason to, because people getting a disease near where the disease is studied is not statistically significant in any way.

                So the strawman argument it is. Let me quickly rip this to shreds:

                1. Lysteria is a Biosafety Level 2 disease, endemic in that it shows up from time to time nationwide, and is unlikely to cause a ruckus. They do, however, profile it gentically when there’s an outbreak, so right there they do investigate. But this is still not equivalent and is a straw man of a disease that people would consider “common” and outside of the poor souls impacted, pretty uneventful…

                2. If a novel virus like airborn Coronavirus, which is a Biosafety Level 3 agent, were to be found in patient zero 8km from a CDC facility studying it, it would trigger a political uproar and investigation. It might get buried with national security, but we all know what that means (much like the military grade anthrax that somehow showed up in envelopes in target politician mailboxes). So your fake equivalence isn’t holding up. If an outbreak of Lymes disease broke out near a CDC facility, it’s unlikely to trigger a panic or investigation. Dengue is LVL 2 containment and is rare enough currently in the US that it might cause concern and investigation. An oubreak of an uncommonly found disease near a CDC facility like Lassa is going to be of interest. We’ve investigated CDC leaks before and those didn’t even trigger events. So your “literally” wrong about “literally never”.

                Oh, and here’s a “checkmate athiests!” on this for you (only joking - there’s no clear evidence yet, but my point is that the PROC is suspect): While politically charged, the house oersight on COVID Origins Hearing Wrap Up: Facts, Science, Evidence Point to a Wuhan Lab Leak is of interest. There’s a bunch of idiotic bullshit red vs. blue in there, but I’ll leave this gem of an outtake:

                Jamie Metzl testified how China’s government destroyed samples, hid records, imprisoned Chinese journalists, prevented Chinese scientists from saying or writing anything on pandemic origins without prior government approval, actively spread misinformation, and prevented an evidence-based investigation.

                and the BBC has Covid: Top Chinese scientist says don’t rule out lab leak indicating the PROC investigated themselves and gave their own lab a thumbs up (without that Lab’s participation) and then kept those result secret.

                In the absence of evidence, we can draw no complete conclusion. But leaking a pandemic causing virus from your only LVL 4 containment lab and saving face by destroying evidence, running a sham investigation that you ALSO cover up seem real problematic in the toxic brew of strict governmental control by PROC on journalists and information, plus a long history of cultural and government corruption. That’s my central thesis and nothing you have stated has refuted this possibility or how a wet market is more likely given both scenarios lack the same evidence. There you have it. I doubt I’m going go convince you that the whole thing is suspect, but any scientist should conclude that it’s a possibility there was a lab leak. I doubt you can conclusively prove that the wet market was the cause when there are thousands of them in china for years before and after the pandemic.

    • tiredofsametab@fedia.io
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      2 months ago

      You don’t even need to eat them; just being in close proximity to them and interacting with them is enough.

      On the other hands, cows, chickens, and humans came together to create a smallpox vaccine, so there’s that at least.

      • TheTechnician27@lemmy.world
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        Yes, it’s just that eating animals has a distinct history of causing horrible pandemics in humans. See e.g. the 1918 H1N1 pandemic which killed tens of millions and was likely started by hogs or chickens farmed in rural Kansas, swine flu which killed hundreds of thousands and whose name speaks for itself, and COVID-19 which killed millions and is well-understood to have originated in a wet market.

        Besides all the other reasons that it’s terrible, animal agriculture is a hotbed for transmitting zoonotic diseases to humans and combining existing human diseases with animal ones.

        • Knock_Knock_Lemmy_In@lemmy.world
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          Points to the bar. “You see this bar? I built this bar with my bare hands from the finest wood in the county. Gave it more love and care than my own child. But do they call me MacGregor the bar builder? No.”

          Points out the window. “You see that stone wall out there? I built that stone wall with my bare hands. Found every stone, placed them just so through the rain and the cold. But do they call me MacGregor the stone wall builder? No.”

          Points out the window. "You see that pier on the lake out there? I built that pier with my bare hands. Drove the pilings against the tide of the sand, plank by plank. But do they call me MacGregor the pier builder? No.

          But you fuck one bat …

      • capital@lemmy.world
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        Would have far less human/animal face time if we didn’t eat so much of them, don’t you think?

        • Knock_Knock_Lemmy_In@lemmy.world
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          Face time probably isn’t the main factor.

          If we didn’t eat so many birds and swine then there would be less animals in close quarters and less chance of new bird/swine flus developing.

          • capital@lemmy.world
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            No doubt that’s a factor. Implied in my comment (though maybe not well conveyed) is that there would be far fewer animals in captivity if we didn’t eat them.

            But what we’re concerned about in the OP and the thread is zoonotic diseases that affect humans. Those surely wouldn’t infect humans at the rate we see today if we weren’t raising them for food and therefore in close proximity to them.

  • hakunawazo@lemmy.world
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    As someone currently down with covid I thought that was state of knowledge long time ago.

    • WanderingVentra@lemm.ee
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      Conspiracy theorists have still been spreading the lab leak theory without proof for awhile now because China is the current scary boogeyman. I get that there was lab there studying these diseases, but guessing isn’t how science works, and the wet markets have been known to be a possible source of diseases for a long time now by scientists. I remember warnings about this scenario coming up awhile ago.

      Lot of diseases come from China probably for similar reasons: it’s crowded and close contacts with lots of animals. No one thought the 1956 flu could be a lab leak, or SARS, or H7N9, etc. People just have conspiracy theories about this one because it turned into the biggest pandemic of them all, which is just the roll of the dice of all the diseases coming out of there.

    • peopleproblems@lemmy.world
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      I think they determined that the virus that spread to humans was bats that transferred to something in the market (aka intermediate hosts). That virus would have spread there, while technically the bats could have infected humans.

    • Knock_Knock_Lemmy_In@lemmy.world
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      Wuhan market didn’t sell bats.

      Also, the only bats with a (96%) similar covid strain were in caves 1000 miles away.

      However, samples from those bats were stored at the wuhan institute of virology.

      • Flying Squid@lemmy.world
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        Very first sentence quoted above. You don’t even have to go to the article:

        A team of scientists say it is “beyond reasonable doubt” the Covid pandemic started with infected animals sold at a market, rather than a laboratory leak.

        No amount of evidence or scientific consensus can convince a conspiracy theorist…

        And yes, I know:

        Despite even highlighting one market stall as a hotspot of both animals and coronavirus, the study cannot provide definitive proof.

        Therefore lab leak, right?

        • Roflmasterbigpimp@lemmy.world
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          The samples were collected by Chinese officials in the early stages of Covid and are one of the most scientifically valuable sources of information on the origins of the pandemic.

          This Part makes me question things a bit. China is not really known for being honest about things happening in China.

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            Questioning things is fine. On the other hand, it’s pretty hard to fake the ability to trace DNA to a specific market stall.

            On top of that, the person I replied to is not questioning. They’ve already decided it’s definitely a lab leak. See all of their other comments.

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            The study itself is quite balanced and honest about data collection. It doesn’t rule out a lab origin like the article claims.

            our study does not rule out human-to-animal transmission, as the sampling was carried out after the human infection within the market. Thus, the possibility of potential introduction of the virus to the market through infected humans, or cold-chain products, cannot yet be ruled out.

  • skuzz@discuss.tchncs.de
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    Duh, it’s so simple. The lab released infected animals to the wet market. All bases covered.

    I’ll take my research grant now.

    (This is all said non-serious to be clear.)

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    I would love to see a picture of that ONE STALL that is thought to have been a hotbed. Whoever runs that stall must be quite a character, too. Golly it’s fun to visit markets in new countries.

    Unless… a plausible alternative to my imagination is that it looks like any other open air fresh meat stall, just with more exotic flesh… And if that’s the case you can keep your photos.

    But just in case. Anyone?

    • crashfrog@sopuli.xyz
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      I mean you’ve seen people with COVID by now; did they look much different?

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        Huh? No, I want to see how chaotic that stall might be. I’m imagining stuff and species of all varieties.

  • JoShmoe@ani.social
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    I suppose its mere coincidence that patient zero was a scientist that was experimenting with covid and its potential to transmit to humans. Pure coincidence.