Have any queer vibes to share? Here’s your place! hexbear-pride

Talk about what’s happening queerly in your life - like coming out, getting HRT, questioning, and all that good stuff.

blob-no No cishets allowed! no-copyright

  • AcidSmiley [she/her]@hexbear.net
    link
    fedilink
    English
    arrow-up
    1
    ·
    edit-2
    1 year ago

    Estrogens all have a very strong first pass metabolism when taken orally. The liver breaks down most of the stuff, which not only reduces efficiency and is a strain on the liver, but also increases risk of blood clots (most of the panic about HRT risks comes from this). This is why sublingual is a good deal safer and more efficient and why other routes like transdermal or injections are generally preferrable, but oral is ok if you regularly get bloodwork done and don’t have other blood clot risks (age, smoking, weight etc.)