The key to these vaccines appears to be proteins in the pancreatic tumors, called neoantigens, which keep the cancer at bay.
  • floofloof@lemmy.caEnglish
    391·
    11 months ago

    In 8 of 16 patients studied, the vaccines activated T cells that recognize the patient’s own pancreatic cancers. These patients also showed delayed recurrence of their pancreatic cancers, suggesting the T cells activated by the vaccines may be having the desired effect to keep pancreatic cancers in check.

    Good news, but the headline lacks nuance.

      • Seytoux@lemmy.one
        71·
        11 months ago

        Same, this big catchy over optimistic and click bait headlines make me automatically really suspicious of the claims. Great news if the second trial goes well

  • MeshPotato@lemmy.world
    173·
    11 months ago

    mRNA? Oh boy the anti vaxxers are going have have their heads explode.

    Great news though as that’s a pretty common cancer.

  • AlexWIWA@lemmy.mlEnglish
    131·
    11 months ago

    mRNA is going to go down in history as the most important medical breakthrough ever. It seems to not have limits

    • golli@lemm.ee
      71·
      11 months ago

      Not all of them, but the most successful from Biontech/Pfizer and moderna are both mRNA based. However there were also others based on protein subunits or viral vectors for example.

        • golli@lemm.ee
          3·
          11 months ago

          If your question is whether crispr gene editing was used by any of the vaccines, then no none of them used it as a direct mechanism.

          However it might have been used somewhere along the line in their creation, e.g. to knock out a gene in the viral vectors. But i couldn’t tell you that with certainty.

            • golli@lemm.ee
              1·
              11 months ago

              Yeah, the possibilities are definitely exciting. But i guess as far as Covid19 vaccines are concerned it was probably a good thing that none required their direct use. As is we already had a ton of missinformation and fearmongering, i don’t even want to imagine how bad it would have been, if gene editing was involved in any direct sense.

    • 👁️👄👁️@lemm.eeEnglish
      51·
      11 months ago

      Yes, mRNA was a huge breakthrough developed by the massive r&d rush from covid vaccine funding. Now we reap it’s benefits as it has a huge amount of applications on a lot of other things too.