The key to these vaccines appears to be proteins in the pancreatic tumors, called neoantigens, which keep the cancer at bay.
  • floofloof@lemmy.caEnglish
    391·
    1 year ago

    In 8 of 16 patients studied, the vaccines activated T cells that recognize the patient’s own pancreatic cancers. These patients also showed delayed recurrence of their pancreatic cancers, suggesting the T cells activated by the vaccines may be having the desired effect to keep pancreatic cancers in check.

    Good news, but the headline lacks nuance.

      • Seytoux@lemmy.one
        71·
        1 year ago

        Same, this big catchy over optimistic and click bait headlines make me automatically really suspicious of the claims. Great news if the second trial goes well

  • MeshPotato@lemmy.world
    173·
    1 year ago

    mRNA? Oh boy the anti vaxxers are going have have their heads explode.

    Great news though as that’s a pretty common cancer.

  • AlexWIWA@lemmy.mlEnglish
    131·
    1 year ago

    mRNA is going to go down in history as the most important medical breakthrough ever. It seems to not have limits

    • golli@lemm.ee
      71·
      1 year ago

      Not all of them, but the most successful from Biontech/Pfizer and moderna are both mRNA based. However there were also others based on protein subunits or viral vectors for example.

        • golli@lemm.ee
          3·
          1 year ago

          If your question is whether crispr gene editing was used by any of the vaccines, then no none of them used it as a direct mechanism.

          However it might have been used somewhere along the line in their creation, e.g. to knock out a gene in the viral vectors. But i couldn’t tell you that with certainty.

            • golli@lemm.ee
              1·
              1 year ago

              Yeah, the possibilities are definitely exciting. But i guess as far as Covid19 vaccines are concerned it was probably a good thing that none required their direct use. As is we already had a ton of missinformation and fearmongering, i don’t even want to imagine how bad it would have been, if gene editing was involved in any direct sense.

    • 👁️👄👁️@lemm.eeEnglish
      51·
      1 year ago

      Yes, mRNA was a huge breakthrough developed by the massive r&d rush from covid vaccine funding. Now we reap it’s benefits as it has a huge amount of applications on a lot of other things too.