• 23 Posts
  • 209 Comments
Joined 1 year ago
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Cake day: June 27th, 2023

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  • From the replies:

    In cGMP and cGLP you have to be able to document EVERYTHING. If someone, somewhere messes up the company and authorities theoretically should be able to trace it back to that incident. Generative AI is more-or-less a black box by comparison; plus how often it’s confidently incorrect is well known and well documented. To use it in a pharmaceutical industry would be teetering on gross negligence and asking for trouble.

    Also suppose that you use it in such a way that it helps your company profit immensely and—uh oh! The data it used was the patented IP of a competitor! How would your company legally defend itself? Normally it would use the documentation trail to prove that they were not infringing on the other company’s IP, but you don’t have that here. What if someone gets hurt? Do you really want to make the case that you just gave Chatgpt a list of results and it gave a recommended dosage for your drug? Probably not. When validating SOPs are they going to include listening to Chatgpt in it? If you do, then you need to make sure that OpenAI has their program to the same documentation standards and certifications that you have, and I don’t think they want to tangle with the FDA at the moment.

    There’s just so, SO many things that can go wrong using AI casually in a GMP environment that end with your company getting sued and humiliated.

    And a good sneer:

    With a few years and a couple billion dollars of investment, it’ll be unreliable much faster.














  • There’s a whole lot of assuming-the-conclusion in advocacy for many-worlds interpretations — sometimes from philosophers, and all the time from Yuddites online. If you make a whole bunch of tacit assumptions, starting with those about how mathematics relates to physical reality, you end up in MWI country. And if you make sure your assumptions stay tacit, you can act like an MWI is the only answer, and everyone else is being un-mutual irrational.

    (I use the plural interpretations here because there’s not just one flavor of MWIce cream. The people who take it seriously have been arguing amongst one another about how to make it work for half a century now. What does it mean for one event to be more probable than another if all events always happen? When is one “world” distinct from another? The arguments iterate like the construction of a fractal curve.)






  • “Quantum computation happens in parallel worlds simultaneously” is a lazy take trotted out by people who want to believe in parallel worlds. It is a bad mental image, because it gives the misleading impression that a quantum computer could speed up anything. But all the indications from the actual math are that quantum computers would be better at some tasks than at others. (If you want to use the names that CS people have invented for complexity classes, this imagery would lead you to think that quantum computers could whack any problem in EXPSPACE. But the actual complexity class for “problems efficiently solvable on a quantum computer”, BQP, is known to be contained in PSPACE, which is strictly smaller than EXPSPACE.) It also completely obscures the very important point that some tasks look like they’d need a quantum computer — the program is written in quantum circuit language and all that — but a classical computer can actually do the job efficiently. Accepting the goofy pop-science/science-fiction imagery as truth would mean you’d never imagine the Gottesman–Knill theorem could be true.

    To quote a paper by Andy Steane, one of the early contributors to quantum error correction:

    The answer to the question ‘where does a quantum computer manage to perform its amazing computations?’ is, we conclude, ‘in the region of spacetime occupied by the quantum computer’.