• Semi-Hemi-Lemmygod@lemmy.world
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    2 days ago

    One must be always drunk, that’s all that matters.

    But what with?

    With wine, with poetry, or with virtue, as you choose.

    But get drunk.

  • OhStopYellingAtMe@lemmy.world
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    3 days ago

    My dearest friend for the past 25 years became a drug addict. She died of an OD on Saturday. Left two young children with no parents. (Dad left years ago). I witnessed her spiral into addiction and destruction over the past 2 years. I couldn’t stop it. I tried.

    If you want to become an addicted to something, please try masturbation or video games.

  • 2ugly2live@lemmy.world
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    2 days ago

    Man, I’ve been tempted. I’ve started saying I’d try a drug if it was ever offered, because I’m too much of a coward to figure out how to get it myself. I have an additive personality, so I know it would kill me and, honestly, I’m fine with that.

  • lath@lemmy.world
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    2 days ago

    Randomly read a click bait article the other day on “How famous people died”. The older ones were alcohol + drug prescription overdose, while the newer ones were fentanyl + cocaine + alcohol.

    Remember people, stay hydrated! Drink your drugs with water like you’re meant to!

  • Blackmist@feddit.uk
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    2 days ago

    Now nothing is fun and nobody trusts to not to steal anything that isn’t nailed down.

  • DudemanJenkins@lemmy.world
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    3 days ago

    Honestly though hallucinogens really need to be more mainstream. Acid completely changed my outlook on life and give me a perspective of life and myself I would never have gotten through therapy or any other depression suppressants.

    It’s also cheap as balls if you find a good plug. 10 bucks for an all day ticket is wild you just have to be with someone you trust with your life who won’t fuck with you.

    • aurorca@lemmy.blahaj.zone
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      3 days ago

      Let’s not forget that acid can be dangerous, I’m still recovering from a traumatic experience I had with acid 10 years ago, I still get flashbacks and panic attacks due to it. I also stopped smoking weed because it would trigger the flashbacks.

      • ditty@lemm.ee
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        2 days ago

        I will never forget the time I did twice as much acid as I intended and it ended up being a heroic dose complete with ego death and everything - not fun. Now I’m very cautious and typically only do microdoses.

      • some_guy@lemmy.sdf.org
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        3 days ago

        I also stopped smoking weed because it would trigger the flashbacks.

        I had this years ago after a series of bad trips (the common denominator turned out to be the presence of a certain person, then things got better). Anyway, hope you can get through to the other side.

    • Cracks_InTheWalls@sh.itjust.works
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      3 days ago

      There are people trying pretty hard to make that happen, though mostly in the context of supervised medical interventions.

      Which I’m here for - while a lot of people do OK (fantastically even) with less structured psychedelic experiences, many do not. A really bad trip can do a number on you, sometimes for a long while.

    • saigot@lemmy.ca
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      3 days ago

      I would suggest growing your own mushrooms as the safest way to be sure they aren’t tainted, it’s pretty easy (the hardest part is keeping things sterile) and you can grow quite a bit at once in a small footprint. In my jurisdiction it’s not even illegal so long as you destroy the final product upon maturity.

      • BlueMagma@sh.itjust.works
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        2 days ago

        Destruction of the final product is also very easy, there are some strong chemicals capable of breaking it down in your own stomach.

    • Jimbo@yiffit.net
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      14 hours ago

      Agreed, doesnt work for everyone tho. I’ve done acid a couple times and it didn’t really change anything for me, other than the actual effects at the time. Perhaps it gave me a slightly larger understanding of the situation we’re all in and how the future is likely to look, but that already weighed on my mind heavily and just makes me sad.

  • beejboytyson@lemmy.world
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    2 days ago

    I was talking about how hard it was for me to cut 5 pounds for my fight. This one guy told me I should take up meth to make weight. Genuinely look at him with utter confusion.

    • Snowclone@lemmy.world
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      2 days ago

      Had a lady demand I hire more meth addicted as ‘‘they work really hard for nothing’’

      I declined her business advice.

    • kandoh@reddthat.com
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      2 days ago

      He’s right. They used to put meth in chocolate and marketed it as a great way for housewives to lose weight while keeping their home tidy.

      • Reucnalts@feddit.de
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        2 days ago

        Didnt know about housewifechocolate i only knew Panzerschokolade, but it wasnt for the wifes at home. But i mean who doesnt need a wife at home who is working at home and still has the energy to work you

  • Dasus@lemmy.world
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    2 days ago

    Alcohol is a depressant my man.

    Neurologically speaking, so in a different context, yeah, but neurological depression also seems to lead to actual depression, the mood disorder, which also show up as neurological depression.

    We really need better imaging tools to measure neurotransmitter activity, would make for several advancements I’d say

    • GiveMemes@jlai.lu
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      2 days ago

      Abuse of any psychoactive drug on the regular leads to depression. It isn’t just this concept of depressant or stimulant or even related in any way. Any stimhead can tell you all about the suicidal ideation inducing comedowns and inability to get anything done after stopping use.

      • Dasus@lemmy.world
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        2 days ago

        Abuse of any psychoactive drug on the regular leads to depression.

        That’s a biased generalisation.

        While abusers of psychedelics are rare, they’re generally manic and psychotic moreso than depressed.

        Yes, depression can be caused by any addiction and abusing stims can cause a lack of neurotransmitter due to exhausting the resources for the body to do so.

        It’s a bit different than using something that’s a direct depressant though.

        • GiveMemes@jlai.lu
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          2 days ago

          Depressant isn’t linked to depression tho. Get that idea out of your head completely. Like seriously go read some neuro textbooks and stop getting your pharmacology info from tiktok. Depressants depress the CNS… depression is a mental illness.

          Also I’ve abused psychs and known a few others that did and I wouldn’t call any of our our activities/side effects manic or psychotic by any means. I know one person who had a family history of schizophrenia that had negative effects like that from their abuse. But just the one. I’d be interested in scholarly articles about the subject tho since I have biased data, and apparently, yours is not, at least from what one would construe from your comment.

          • Dasus@lemmy.world
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            2 days ago

            Isn’t linked?

            That’s just wrong. Correlation is a link. The long term high dose use of any CNS depressant correlates with actual depression (the psychological issue [I added the brackets because you seemed to miss when I specified the difference earlier.])

            Oh wow, an anecdotal story, well that just proves what you’re saying is 100% correct.

            Science couldn’t possibly disagree

            “Pure” psychedelics like LSD and psilocybin rarely cause any sort of abuse, really, but I’ve been on a drug abuse closed ward and the manic people were generally in there because of CNS stimulants of all sorts. Psychedelics are just less likely to yield any long-lasting harmful effects compared to say smoking crack or snorting meth.

            So yeah, while a CNS depressant isn’t the a thing that directly causes psychological depression as such, you can probably see how they’re linked from the following analogy; imagine that I tie your legs together. That doesn’t remove your ability to walk, per se, as long as you remove the restraints. But if no-one removes them for 50 years, do you think you’d walk as well as before?

            In much the same way, yes, CNS depressants are linked to depression, and alcohol and benzos are the clearest examples.

            https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238014/#:~:text=Studies have reported that prolonged,medications for non-pain symptoms.

            https://americanaddictioncenters.org/alcohol/risks-effects-dangers/depression#:~:text=Alcohol can not only lead,reducing or stopping alcohol use.

            • GiveMemes@jlai.lu
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              1 day ago

              This one is a CNS stimulant.

              https://www.verywellmind.com/adderall-for-depression-4845418

              So is this

              https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2021.808807/full

              They’re both linked to depression too. My point is that you need to get this idea of correlating the terms because of how they look similar out of your head. It’s a result of drug abuse (addiction/overuse) and the consistent changes caused by that in brain chemistry, causing negative effects when they aren’t affecting you. It’s not a result of it being a depressant vs a stimulant that you’re addicted to. A depressant, when not abused, relieves symptons of depression (and even when abused, often relieves them upon intake). Not going to get into how stimulant mania is likely caused mostly by lack of sleep, but you can look into it if interested.

              And you’re right that psychedelic abuse hasn’t been linked to increased depression or anxiety… mostly because there’s no research on it whatsoever. In fact, almost all of our studies on drug abuse and addictiveness are incredibly flawed in the first place. That doesn’t make your anecdotal experience from a drug ward any more powerful tho, especially as it’s going to self select for people with mania as they are more likely to both be committed by the state and by their family or friends, more likely to cause people to take notice and sit them down, etc.

              Analogies are great when it’s not medicine. Medicine is really fucking complicated tho. We can have a veritable chemical pathway and successful trials in animal testing and still end up with a result we shouldn’t expect.

              My point is not that CNS depressants don’t cause depression from abuse, but that it’s just a result of abusing drugs, not the fact that they’re a depressant class drug.

  • terminhell@lemmy.world
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    3 days ago

    Vitamin D deficiency is a silent widespread issue for a lot of people. Had a battle with it a few years ago. Was tired no matter how much sleep I got, had negative motivation to do anything. Libido all but disappeared, and finally sought a doctor visit when I started have suicidal thoughts.

    Turns out I just needed more sunshine and 50kiU once a week for a month.

    • Dozzi92@lemmy.world
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      2 days ago

      Vitamin D toxicity is also a big problem, and doctors have been overprescribing supplementary vitamin D for years. Feels almost like a joke, you’re damned if you do, damned if you don’t.

    • MewtwoLikesMemes@lemmy.world
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      3 days ago

      kiU

      I know vitamins are typically measured (at least here in the US) in International Units (IU), but I’ve never heard of “kiU”.

      What’s that short for?